Eppendorf & Science Prize for Neurobiology

The international Eppendorf & Science Prize for Neurobiology is awarded annually to one young scientist who is not older than 35 years for the most outstanding neurobiological research based on methods of molecular, cellular, systems, or organismic biology conducted by him/her during the past three years.

Prize money: US$ 25,000

Eppendorf & Science Prize Winner 2025

Congratulations to Cheng Lyu, Ph.D., Postdoctoral Fellow at the University Stanford, California, USA, on winning the 2025 Eppendorf & Science Prize.

Dr. Lyu won the Prize for his work on rewiring the olfactory neural circuit in fruit flies, which alters the animal’s courtship behavior.

Cheng Lyu’s research uncovered how the fly’s olfactory circuit reduces a seemingly intractable 3D wiring problem into simpler 1D choices. By systematically tracing, quantifying, and perturbing neuron development across many cell types, Cheng and his colleagues revealed that partner selection occurs along constrained trajectories, greatly simplifying the molecular codes for specificity. Building on this framework, he demonstrated that by tuning the combinatorial balance of attraction and repulsion, it is possible to rewire single neuron types to form alternative connections.

Read more about Cheng Lyu’s work here.

Finalists

Dr. Constanze Depp
Boston Children’s Hospital, Harvard Medical School, Broad Institute of MIT and Harvard, Cambridge, USA

Sara Mederos, Ph.D.
Sainsbury Wellcome Centre, University College London, London, UK