Maurice Michel: How to teach an enzyme “to whistle”
In the new Nature podcast, Maurice Michel, winner of the Eppendorf Award for Young European Investigators 2023, talks to science journalist Adam Levy about his research. Binding a small molecule to the active site of a DNA repair enzyme not only increases its activity, but also prompts it to carry out a reaction not found in the free protein leading to enhanced DNA repair after oxidative damage. These groundbreaking discoveries may have far-reaching applications in the treatment of cancer or age-related degeneration. Maurice Michel is an assistant professor at Karolinska Institutet in Stockholm, Sweden.
Here you can listen to the podcast.