Eppendorf licenses technology for thermal cyclers to SensoQuest
Hamburg, September 15, 2014 – Eppendorf AG has licensed patents covering gradient technology for thermal cyclers to SensoQuest GmbH, including German patent Nos. DE 196 55 282 and DE 196 55 141. Eppendorf utilizes the technology in its Eppendorf Mastercycler® pro gradient and Mastercycler nexus gradient models.
Next Automated NGS Library Preparation Method for the Eppendorf epMotion: TruSeq® Stranded mRNA
Hamburg, September 2014
Today Eppendorf announces the availability of the epMotion automation method for Illumina’s TruSeq Stranded mRNA library preparation kit for next-generation sequencing as “Illumina Qualified.” “Illumina Qualified” indicates that Illumina’s analysis of libraries prepared with this epMotion method has shown the libraries to perform comparably to those prepared manually. For next generation sequencing systems a variety of sample preparation kits are available. These kits are needed to convert either DNA or RNA samples into sequencing ready libraries, a procedure that includes many steps and can be time consuming. RNA sequencing requires additional steps – either the depletion of unwanted ribosomal or the positive selection of mRNA from total RNA samples. Due to the complexity of the library construction methods, automation is regarded as highly useful.
The epMotion method can be used for the automated construction of 8, 16 or 24 libraries starting with 100 – 1000 ng of total RNA together with Illumina’s TruSeq Stranded mRNA kit. The overall hands-on time is less than 1.5 hours, while the total run time of the entire procedure is ~11.5 hours for 24 samples. Minimized hands-on time & high reproducibility with this automated method help to streamline and standardize the sequencing workflow.
Additional automated methods for NGS library preparation from Illumina are currently in development.
New epMotion 96 dramatically improves productivity and efficiency when working with 96 well plates
Hamburg, August, 2014
The new epMotion 96 from Eppendorf provides an ideal, time-saving solution for scientists undertaking the repetitive task of working with 96 or 384 format microplates or deep-well plates within life science research laboratories and pharmaceutical and industry laboratories. The epMotion 96 allows easy, rapid handling with high precision and accuracy compared to multi-channel manual pipettes and thanks to its ability to dispense into all 96 wells at the same time, makes it possible to simultaneously start or stop a biological assay for all wells in a plate. The system also makes the task more comfortable and efficient for laboratory workers by greatly reducing the risk of repetitive stress injury caused by manual pipetting.
The epMotion 96 has a large volume range between 0.5 and 300µL using only one head or system so there is no need to switch pipette heads or employ a second device to achieve all volumes. In addition, several electronic pipette features are available including multiaspirate, multidispense, pipette and mix and programming combinations, opening up a whole range of applications and methods to help users get the exact results they need.
Ease of use is ensured with the proven Eppendorf software concept and touch screen control. Its small footprint makes the epMotion 96 ideally suited for use in busy laboratories.
“The latest addition to the Eppendorf epMotion range allows pipetting tasks to be completed faster and more precisely,” said Dr. Carsten Buhlmann, International Product Manager at Eppendorf. “With new epMotion 96, you can pipette entire 96-well plates at once, which makes a huge difference to productivity and efficiency.”
For more information on the epMotion 96, please visit www.eppendorf.com
Product, performance and packaging: New Eppendorf cell culture consumables deliver quality in all
Hamburg, July 2014
The new Eppendorf Cell Culture Consumables offer a new dimension of safe, reproducible and reliable cell culture work. Scientists and technical personnel in the field of cell culture have a strong need for easy, safe and reliable products with improved handling that help prevent contamination. The latest products from Eppendorf deliver exceptional levels of product purity and security, as well as improved, ergonomic and safe handling of cell cultures and advanced protection against contamination. The new, easy resealable packaging concept complements the products’ unique features and performance.
Eppendorf Cell Culture Consumables are made from ultraclear virgin polystyrene, which complies with USP class VI for highest purity. Cell Culture Consumables have a ISO class /GMP class C clean room production standard and a sterility assurance level (SAL) of 10-6 as well as batch specific 3rd party quality testing ensuring exceptional product and sample safety.
Innovative technologies in Eppendorf Cell Culture Consumables deliver ultimate ease of use. New high efficiency air filter technology in Eppendorf flasks provides improved contamination protection, while ConvexAccess™ neck geometry allows more ergonomic handling and facilitated entry into flasks. Meanwhile, a corrugated handling ring and new SplashProtect™ ring in dishes deliver safe, confident handling and better protection against contamination. Finally, Eppendorf’s new chimney well design in plates minimizes the “edge effect” and leads to more reproducible assay results.
Many cell culture applications require the constant use of a sterile safety cabinet, which often has a limited amount of space available. Eppendorf’s new packaging concept addresses this limitation through easy opening, truly resealable and shrinkable design, allowing safe storage and requiring less space, while an innovative tray allows easy removal of the products from the box and safe workflows.
For more information, please visit www.eppendorf.com/ccc
Eppendorf & Science Prize Winner 2013 in Hamburg
Hamburg July 2014 - The Israeli scientist, Michael Yartsev, CV Starr Research Fellow at the Princeton Neuroscience Institute and 2013 winner of the Eppendorf & Science Prize for Neurobiology, visited Eppendorf headquarters in Hamburg in July 2014. On this occasion Dr Yartsev gave a talk about his ground-breaking work. He uses an unusual animal model, the bat, to study the underlying neural mechanisms of spatial memory and navigation in the mammalian brain. His approach allows for both a comparative examination of current hypotheses as well as novel insight into long standing questions in the field. His work also underscores the potential benefits of using new animal models in neuroscience.
The international US$25,000 Eppendorf & Science Prize for Neurobiology is awarded jointly by Eppendorf and the journal Science. All young scientists who are 35 years of age or younger and who have made outstanding contributions to neurobiological research are invited to apply. The 2014 winner of the Prize will be announced in the fall. The next deadline for applications is June 15, 2015. For more information, visit www.eppendorf.com/prize.
With the new ThermoMixer® F0.5 and F2.0 Eppendorf introduces two new experts for sample preparation
Hamburg, June 2014
Ever since the launch of the company’s first performance-defining Mixer and the first Thermostat in 1964 Eppendorf has been at the forefront of mixing and temperature control technology for µL volumes. Thanks to Eppendorf’s continuous development, an exciting new generation of Temperature Control and Mixing Instruments is now set to impress with excellent mixing results, outstanding temperature management and the ergonomics and simplicity essential for routine use in a busy laboratory.
The excellent mixing results of the new Eppendorf ThermoMixer® F0.5 and F2.0 (two-in one instruments for combined mixing and incubating) are provided by the unique 2DMix-Control. This is the proven technology from Eppendorf ThermoMixer® C, F1.5 and FP which ensures fast and efficient mixing in just seconds. Controlled circular movements achieve thorough mixing of liquids in even the smallest volumes, while the anti-spill technology prevents lid wetting and cross-contamination.
These instruments were specifically developed for applications in tube formats 0.5 mL and 2.0 mL and extend the product portfolio of the Eppendorf ThermoMixer® family.
For best temperature control performance, Eppendorf also offers the unique Eppendorf ThermoTop® for these instruments, a heated lid with condens.protect technology. This easy-to-use ThermoTop reliably prevents condensation forming on the tube lid and wall, and in addition supports temperature homogeneity of the thermoblocks to ensure excellent reaction conditions. Simple, wireless handling and its automatic recognition render the Eppendorf ThermoTop® indispensable for optimal performance.
Predefined program and temperature keys provide fast and easy access to the most frequently used temperature parameters. With simplicity and ease of use at heart, Eppendorf designed the new ThermoMixer®F0.5 and F2.0 to provide time-saving, stress-free operation and a pleasant working environment.
For tube flexibility in dry incubation, Eppendorf offers the Eppendorf ThermoMixer® C and ThermoStat C, which are operated together with Eppendorf SmartBlocksTM.
For more information on the Eppendorf ThermoMixer® family please visit www.eppendorf.com/thermomixer-f.
Reorganization of the Executive Board of Eppendorf AG
Hamburg, Germany, June 13, 2014
The Executive Board of Eppendorf AG is reshaping in order to be optimally equipped to meet the future demands of the market.
Dr. Dirk Ehlers, Chairman of the Executive Board of the Eppendorf Group, will leave the company by mutual agreement. Detmar Ammermann (Chief Financial Officer) will represent the Executive Board as its speaker. As of July 1, 2014, Dr. Ralf Hermann (Marketing) and Dr. Wilhelm Plüster (Technology) will join the Executive Board as new members, serving alongside Dr. Michael Schroeder (Sales) and Dr. Heinz Gerhard Köhn (Quality Management and Technology Projects).
Presentation of the 2014 Eppendorf Award for Young European Investigator to Madeline Lancaster
- This year’s research prize awarded by Eppendorf goes to Austria
Heidelberg/Hamburg, May 23, 2014 – The American scientist Madeline Lancaster, Ph. D. (Marie Curie Postdoctoral Research Fellow, Laboratory of Jürgen Knoblich at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences, IMBA, Vienna, Austria) has won the 2014 Eppendorf Award for Young European Investigators.
Madeline Lancaster, born 1982, receives the Eppendorf Award for her work showing that complex neuronal tissues resembling early states of fetal human brain can be created in vitro from pluripotent stem cells. Her groundbreaking experiments allow for the first time to recapitulate the development of brain structures in a three-dimensional organoid. Madeline Lancaster also documented that diseases caused by aberrant development such as microcephaly can be reproduced in the organoid culture. These discoveries allow for novel approaches towards the understanding of neurological diseases.
With the 15,000 Euro Eppendorf Young Investigator Award which was established in 1995, Eppendorf AG honors outstanding work in biomedical research and supports young scientists in Europe up to the age of 35. The Eppendorf Award is presented in partnership with the scientific journal Nature. The Award winner is selected by an independent committee composed of Prof. Reinhard Jahn (Max Planck Institute for Biophysical Chemistry, Göttingen, Germany), Prof. Dieter Häussinger (Clinic for Gastroenterology, Hepatology and Infectiology, Düsseldorf, Germany), Prof. Maria Leptin (EMBO, Heidelberg, Germany) and Prof. Martin J. Lohse (Institute for Pharmacology and Toxicology, University of Würzburg, Germany).
The Award ceremony took place at the EMBL Advanced Training Centre in Heidelberg, Germany, on May 22, 2014. The laudatio honoring Madeline Lancaster’s achievements was held by the jury chairman Prof. Reinhard Jahn.
Madeline Lancaster: “The human brain exhibits dramatic evolutionary and developmental expansion, a process that has been difficult to examine in traditional animal models. In order to gain insight into this uniquely human process, my work focuses on the use of a 3D in vitro model system of human brain development, termed cerebral organoids, to examine regulators of brain size in the context of human evolution and neurodevelopmental disease.
This Award is a recognition of the potential of stem cell technologies to model human development and disease. It is a testament to the power of combining diverse fields to shed light on key questions, and it would not have been possible without the important contributions of our collaborators, and the supportive environment of the Knoblich group and IMBA.”
More information at www.eppendorf.com/award
Eppendorf: Sales stable in 2013
- Income from operations (EBIT) of approximately €94 million
- Well equipped for 2014 with many new products
Hamburg, April 10, 2014 – In fiscal year 2013, the Eppendorf Group achieved sales of €502.7 million (prior year: €520.2 million). When adjusted for currency effects, sales were only slightly lower than in the previous year (-0.4%). Income from operations (EBIT) decreased to €93.8 million (prior year: €101.5 million), and 2013 net income declined to €67.5 million (prior year: €70.6 million).
The slight drop in sales took place against the background of difficult market conditions – especially in the publicly financed research sector in the USA – that could not be completely evened out by growth in Europe and Asia. At the same time, the company added more than 100 employees to its staff to develop its international sales and service structures even further. Expenses for research and development increased only slightly to €28.2 million (prior year: €27.5 million), since many new products were introduced in 2013 or will be launched soon.
"In spite of the extremely difficult market situation in segments that are important to our business, in 2013 we continued to invest in our organization, products, infrastructure and brand," said Dr. Dirk Ehlers, Chairman of the Executive Board of Eppendorf AG. "The increasing breadth of our position and our market presence are the foundation of our sustainable course for growth."
New Eppendorf FemtoJet® 4i and FemtoJet® 4x electronic micro-injectors deliver high levels of reproducibility and precision
Hamburg, April 2014
Eppendorf has introduced its latest electronic microinjectors, the FemtoJet® 4i and FemtoJet® 4x. The new systems are perfectly suited for all research laboratories wishing to inject small to intermediate volumes, from femtoliters to microliters, precisely and reproducibly. With simple operation and a wide range of functionalities, the FemtoJet 4i and FemtoJet 4x make otherwise intensive processes convenient and easy to undertake, with limited amount of input and training.
With a built-in compressor, the FemtoJet 4i is the ideal solution for injecting small volumes of up to ~100pL into adherent and suspension cells. For users wishing to inject larger volumes or longer series at higher pressures, the FemtoJet 4x employs an external pressure supply to deliver the precise and continuous pressure required. The systems can also be easily coupled with the existing Eppendorf InjectMan® 4 and TransferMan® 4r, for rapid and efficient microinjections into delicate cells. This not only simplifies researchers’ daily tasks, but speeds up workflows.
The new FemtoJets have exceptionally low noise emissions and a small footprint and also benefit from Eppendorf’s premium levels of design, making them ideal for use in busy laboratories. When researchers wish to carry out gentle microinjection procedures, including pronuclear injection and serial injections, the new FemtoJet 4i and FemtoJet 4x provide an ideal solution.
For more information on the FemtoJet® 4i and FemtoJet® 4x, please visit www.eppendorf.com.